Skincare and Longevity: Routine and Recommendations [2025]

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If you’re interested in longevity, you might be curious about a skincare routine so that your physical appearance matches your biological age.

As part of a commitment to extending his lifespan, it’s wise to implement a skincare protocol to protect against aging and UV-related damage.

In this post, we’ll break down a detailed longevity skincare routine, the products to get started, and the experimental techniques some experts are testing today.

Let’s dive in!

Top picks
Face cleanser: CeraVe Face Wash
Face Moisturizer Morning: CeraVe AM Facial Moisturizing
Face Moisturizer Evening: CeraVe PM
Body Moisturizer: CeraVe Moisturizing Cream
Sunscreen: EltaMD UV Clear

Skincare Routine for Longevity

We reviewed interviews, videos, and scientific research to identify which compounds and products to use to protect and enhance your skin.

Face Wash

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01/06/2025 12:29 am GMT

Washing the face twice a day is a key first step to any skincare routine.

We recommend a gentle, non-drying cleansers that won’t strip the skin.

Look for hydrating ingredients like glycerin and avoid harsh surfactants like SLS.

CeraVe AM Face

Most Popular
01/06/2025 12:29 am GMT

CeraVe AM Facial Moisturizing Lotion contains hyaluronic acid, niacinamide and ceramides to hydrate while providing broad spectrum SPF 30 sun protection.

This lightweight, oil-free lotion moisturizes without clogging pores.

CeraVe Body

Most Popular
01/06/2025 12:29 am GMT

Apply a moisturizing body lotion like CeraVe after bathing to nourish dry skin.

Look for hydrating ceramides and hyaluronic acid plus skin-reinforcing niacinamide.

Fragrance-free formulas are less irritating for sensitive skin.

CeraVe PM Face

CeraVe PM Facial Moisturizing Lotion is an ultra-light, non-comedogenic night cream with skin-restoring niacinamide and ceramides.

This oil-free, fragrance-free formula won’t clog pores while deeply hydrating your skin overnight.

UVA/UVB Mineral Sunscreen

Daily broad spectrum SPF 30+ sunscreen is crucial for preventing UV damage that leads to accelerated skin aging and hyperpigmentation.

We recommend mineral sunscreens with zinc oxide and titanium dioxide rather than chemical UV filters which can irritate sensitive skin.

Tretinoin 0.1%

Applying a prescription retinoid like tretinoin nightly exfoliates and stimulates collagen to reduce fine lines, even tone and smooth texture over time.

Start with a low percentage like 0.01% and slowly build up tolerance to this powerful but potentially irritating vitamin A derivative.

Consult a dermatologist prior to pursuing this option.

UV Environmental Filters

This refers to physical barriers to protect the skin from damaging UV rays.

One example, is protective gloves or sunglasses that some opt to wear while driving.

Other Active Creams

Serums and treatment creams with active ingredients target specific concerns like wrinkles, dark spots, breakouts, etc.

Antioxidants like vitamin C, vitamin E and ferulic acid defend against daily skin damage from pollution and UV exposure.

Niacinamide improves texture and tone.

Use them after cleansing and before heavier moisturizers.

Longevity and Skincare Experiments

Bryan Johnson Skincare Routine

Red Light Therapy

Red light therapy exposes the skin to red and infrared wavelengths that have anti-aging and rejuvenating benefits.

You can start with LED panels emitting 630nm red light and 830nm near-infrared light.

Bestqool Red Light Therapy Device 100 Clinical Grade Dual Chip LEDs, 660nm 850nm
4.6
$319.00
Pros:
  • High-powered unit, comparable with expensive brands
  • Option to choose red light, infrared light, or both
  • Integrated digital timer
01/05/2025 01:26 pm GMT

This stimulates collagen and elastin production, reduces inflammation, and improves skin tone and texture.

Related: Best Red Light Therapy Bed

Microneedling With HA Serum

Microneedling is a procedure that uses tiny needles to create micro-injuries in the skin which triggers collagen production and skin regeneration.

One experimental technique uses very fine needles that don’t cause bleeding paired with a hyaluronic acid serum which provides deep hydration.

The microneedling creates pathways for the HA to penetrate deeper into the skin, resulting in plumper, more hydrated skin with reduced signs of aging.

Cutera Excel V

The Cutera Excel V is a laser treatment that uses two different wavelengths of light to treat vascular and pigmentation issues.

The Coolview setting uses 1064 nm light to target redness from broken capillaries or rosacea.

The Genesis setting uses 1320 nm light to target brown spots and uneven pigmentation.

This dual treatment can improve both redness and brown spots in one session with minimal downtime.

Fotona Dynamis Pro 4D

The Fotona Dynamis Pro laser system offers a variety of different treatments to target various skin concerns.

The 4D treatment uses four different modes – QCW Nd:YAG, Er:YAG, Long Pulse Nd:YAG and a Non-Ablative Mode – to provide skin rejuvenation and tightening.

There are other trial protocols offered by the Fotona system to treat specific issues like acne scars, sun damage, fine lines, and more.

Microbotox injections for pore shrinkage

Microbotox involves using very low doses of diluted Botox injected into the pores on areas like the nose, chin or cheeks.

The Botox relaxes the muscles around pores allowing them to shrink and appear smaller over time.

This off-label use of Botox can provide a minimally invasive option for reducing the appearance of enlarged pores.

Sculptra

Sculptra is an injectable made from poly-L-lactic acid that stimulates collagen production to gradually add volume under the skin.

It can be used to treat facial fat loss and volume loss in areas like temples, cheeks and chin.

Sculptra could help to provide subtle volume enhancement and smoothing of wrinkles and folds.

PRF

PRF (platelet-rich fibrin) therapy uses concentrated growth factors from the patient’s own blood to promote skin rejuvenation.

A blood sample is processed to isolate the PRF serum which is then injected into areas of the face to stimulate new collagen, improve tone and texture, and reduce the appearance of wrinkles.

Renuva

Renuva involves harvesting a patient’s own fat via liposuction, then processing and reinjecting the fat to add volume to areas like the face, hands or buttocks.

This autologous fat transfer procedure uses the patient’s own tissue so there is no chance of rejection.

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About the Author

Drew Wilkins is a fitness and nutrition expert with a Master's in Biokinesiology (emphasis in Sports Science) from the University of Southern California and over a decade of experience as a personal trainer, nutrition consultant, and wellness coach. An avid surfer and soccer player, he brings a unique perspective to his research, advocating for a balanced approach to health that includes physical fitness, nutrition, and mental well-being.

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