{"id":1930,"date":"2024-01-18T23:20:21","date_gmt":"2024-01-19T03:20:21","guid":{"rendered":"https:\/\/pursueperformance.com\/?p=1930"},"modified":"2024-06-16T21:38:09","modified_gmt":"2024-06-17T01:38:09","slug":"andrew-huberman-cholesterol","status":"publish","type":"post","link":"https:\/\/pursueperformance.com\/andrew-huberman-cholesterol\/","title":{"rendered":"Andrew Huberman Cholesterol Science & Recommendations"},"content":{"rendered":"

Andrew Huberman, an acclaimed neuroscientist, and tenured Stanford professor, discussed the topic of cholesterol with Dr. Peter Attia, reviewing the latest science.<\/p>\n\n\n\n

Cholesterol is one of the most widely discussed<\/strong> and debated <\/strong>health metrics.<\/p>\n\n\n\n

However, much of the conventional wisdom is based on outdated science<\/strong> or misconceptions<\/strong>.<\/p>\n\n\n\n

In this post, we will share Huberman’s key cholesterol insights<\/strong> into actionable takeaways to help you understand mistakes to avoid<\/strong> and a multi-pronged plan<\/strong> for optimizing this critical health metric.<\/p>\n\n\n\n

Let’s dive in!<\/p>\n\n\n\n

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Top Pick<\/strong>
Cholesterol Support: CRYSTAL PEAKS NUTRITION<\/strong><\/a><\/p>\n<\/blockquote>\n\n\n\n

<\/span>Huberman Cholesterol Overview<\/span><\/h2>\n\n\n
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\"Heart,<\/figure><\/div>\n\n\n

<\/p>\n\n\n\n

Cholesterol<\/strong> serves vital structural, hormonal, and digestive roles fundamental to sustaining health.<\/p>\n\n\n\n

Given these critical functions, it makes sense that the body tightly regulates cholesterol production<\/strong>, absorption<\/strong>, and transport <\/strong>to ensure adequate amounts for tissue needs systemwide.<\/p>\n\n\n\n

Cell Membrane Integrity<\/h3>\n\n\n\n

First, cholesterol provides crucial structure and flexibility to the membranes of cells throughout the body.<\/p>\n\n\n\n

Cell membranes act as gatekeepers<\/strong>, controlling what can enter and exit the cell.<\/p>\n\n\n\n

Cholesterol enables membranes to be selectively permeable<\/strong>, properly regulating the transport of ions, nutrients, and waste products into and out of cells.<\/p>\n\n\n\n

Without adequate cholesterol, cells lose their ability to maintain internal homeostasis<\/strong>.<\/p>\n\n\n\n

Hormone Production<\/h3>\n\n\n\n

Second, cholesterol serves as the precursor<\/strong> from which the body synthesizes several vital hormones, including testosterone, estrogen, cortisol, and vitamin D.<\/p>\n\n\n\n

Testosterone and estrogen regulate sexual development<\/strong> and function, while cortisol <\/strong>manages metabolism <\/strong>and stress response<\/strong>.<\/p>\n\n\n\n

Vitamin D<\/strong> supports bone health and immune function.<\/p>\n\n\n\n

Without sufficient cholesterol, hormone synthesis suffers<\/strong>, and health deteriorates on multiple fronts.<\/p>\n\n\n\n

Digestion and Absorption<\/h3>\n\n\n\n

Finally, cholesterol is a core structural component of the bile acids produced by the liver.<\/p>\n\n\n\n

Bile acids are constantly released from the gallbladder into the small intestine to emulsify fats and enable digestion and absorption of not only fats but also the fat-soluble vitamins A, D, E, and K<\/strong>.<\/p>\n\n\n\n

Without adequate bile acid production, fat absorption is impaired, and nutritional deficiencies<\/strong> can arise over time.<\/p>\n\n\n\n

<\/span>Huberman LDL Cholesterol vs. ApoB<\/span><\/h2>\n\n\n
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\"Huberman<\/figure><\/div>\n\n\n

<\/p>\n\n\n\n

LDL cholesterol has long been branded as “bad” cholesterol<\/strong>.<\/p>\n\n\n\n

However, Attia explains that LDL merely transports cholesterol<\/strong> in the bloodstream when cells need to share cholesterol with each other.<\/p>\n\n\n\n

Rather than LDL cholesterol level alone, the total number of LDL particles, measured via the ApoB test<\/strong>, is most predictive of cardiovascular disease risk<\/strong>.<\/p>\n\n\n\n

Related: Andrew Huberman InsideTracker Recommendations<\/a><\/strong><\/p>\n\n\n\n

Understanding ApoB<\/h3>\n\n\n\n

ApoB measures particles containing both LDL and VLDL<\/strong> cholesterol.<\/p>\n\n\n\n

These particles drive the atherosclerotic plaque formation<\/strong> underlying heart disease.<\/p>\n\n\n\n

The lower the ApoB particle number<\/strong>, the lower the risk.<\/p>\n\n\n\n

LDL cholesterol level can be deceiving<\/strong> on its own because it focuses only on the cholesterol content of LDL particles.<\/p>\n\n\n\n

But it’s the total LDL particle number<\/strong> that correlates with heart disease progression.<\/p>\n\n\n\n

ApoB provides the most accurate measurement<\/em> of this atherogenic particle burden.<\/p>\n\n\n\n

Focusing on ApoB over LDL cholesterol level provides a much more accurate picture<\/strong> of true cardiovascular disease risk.<\/p>\n\n\n\n

<\/span>Peter Attia Cholesterol Recommendations<\/span><\/h2>\n\n\n\n
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